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For thousands of years, people from all over the world have been using plant extracts, toad skin, snail skin and mucus to stimulate the healing of epidermal wounds, burns and infectious diseases and to remove acne scars. Recent Western medical science has started to unlock the magic of these natural methods of curing. The findings of biologically active peptides and glycoproteins in snail body and secretions (Kubota Y et al., 1985) in frog skin (Zasloff, 1987) and in plants (Broekaert et al., 1995) explains the positive effects of these treatments. Those bioactive peptides are highly effective against a range of microorganisms and are thus named antimicrobial peptides.

Such magic of Nature is also part of our own skin defense mechanism. Some animals are born with antimicrobial peptides deployed as an important defense against microbial infection (Gallo and Nizet, 2003). The skin is a defensive wall between internal organs and the outside environment. It is exposed daily to thousands of potential pathogens, a host of toxins and physical stress. In order to bear these challenges, skin functions as a physical barrier and has an active defensive role in the identification of microbes as well as in the production of cytokines and defense molecules like antimicrobial peptides.

The number of reports showing the existence and up regulation of antimicrobial peptides in human skin is increasing and reflects the significance of these peptides in skin protection and treatment. Researchers have focused on recreating its bioactive elements (by biosynthesis) in the laboratory.

That is a promising new venue for research and creating effective drugs, but bringing a medication to clinical trial is time consuming and costly. Every thing from discovery, identification, synthesis and clinical trials, must be estimated as expenses that will bring a drug to market. Additionally, this process can also take 10 or many more years to accomplish.

Fortunately chance and keen observation of the effects of the snail serum on the small skin lesions of people who manipulated snails, has allowed to persevere in making the extract available naturally in the form of a topical product for skin problems and to remove acne scars. Producers noticed that the workers they took care of the snails (in Chile) would have smoother skin. Those suffering from acne, acne scars and rosacea would also show signs of improvement in their skin condition. The fact that the snail extract contains glycoproteins and peptides that kill bacteria and organically induce the synthesis of endogenous antimicrobial peptides has been known since 1985. Due to a renewed interest in natural products for skin care, lotions containing snail serum have become more available. The same ingredient provides an answer to the pressing question of how to get rid of acne scars quickly.